The following are tips that helped me alleviate 50 symptoms and reduce my sensitivities a lot.
I am a medical doctor or health practitioner - so these tips are meant to treat or replace proper medical attention
Treatment in my opinion should primarily focus on managing Central Sensitivity and reducing the neurotransmitter glutamine and NMDA activity - hyper excitability, these can significantly contribute to heightened pain, prolonged pain, wide spread pain (allodynia, hyperalgesia, hyperpathia) and hypersensitivity to chemicals, stimuli and stress.
Heightened NMDA activity and glutamine (glutamate) are involved in the self maintaining NO/OONO inflammatory disease cycle postulated by biochemist Dr Martin Pall, it is worsened by what I call Toxicity, inflammation and stress (TIS). It has also been connected to "sensitisation" and "kindling" which is worsened by continued exposures to triggering substances and stimuli.
Managing environment and reducing exposure to stimuli and chemicals is very important
it can disrupt the kindling process and reduce sensitivities. (I call this the V5 treatment approach- explained at www.50symptoms gone -also found at my blog 50 symptoms gone are product recommendations and other resources you may find helpful)
For some people anticonvulsant medications such as Gabapentin can be helpful
Tricyclics is another option, however as people with MCS generally have quite severe medicine sensitivity these need to be started on low doses and increased slowly under medical supervision to test for tolerance. This is also recommended to people with chronic fatigue syndrome by the Centers for Disease Control and Prevention (CDC)
Supplement protocols like the Neural Protocol promoted by both Dr Grace Ziem and Dr Martin Pall, have proven beneficial for some people with MCS however harmful for others.
For people with more severe phenol-salicylate intolerance they can worsen symptoms and sensitivities. People with more severe phenol-salicylate intolerance and other pharmacological food intolerance (e.g. MSG, aspartame, glutamine, amines) may experience "drug resistant" depression according to Psychiatrist Dr Gordon Parker and may experience very heightened side effects to "psychogenic" drug therapies.
Phenol-Salicylate intolerance and pharmacological food intolerance affects at least 1 in 3 people with CFS and chemical sensitivities quite severely according to Dr Robert Loblaly Director of the RPAH Allergy Unit.
Until phenol-salicylate intolerance is ruled out I personally think it is important to a take a precautionary approach and assume it is a problem as continuing to take agents and eat foods high in phenols-salicylates has been shown to further deplete enzymes (particularly those that affect Phase 2 liver detoxification-sulfation) and increase toxicity . Some supplements more suitable for people with phenol-salicylate intolerance are listed in the RPAH Allergy Unit personal care and hygiene guide for people with scent and chemical sensitivity. Non phenolic supplements such as B12 methylcobalamin, tri-salts and non plant based toxin binders such as charcoal tabs and zeolites (taken at least 1 hr either side of food so as not to interfere with nutrient absorption) have been reported beneficial by many.
For some people detoxification methods such as FIR Sauna Therapy can be useful if engaged in very safely
however, other detoxification methods can be problematic due to enzyme depletion and liver detoxification impairment and are generally not recommended. Detoxification methods that provoke rapid detoxification such as fasting and high quantities of juices are not generally recommended. Very restricted calorie diets, that promote rapid weight loss should also be avoided according to Dr Grace Ziem.
When it comes to Sauna Therapy Dr Sarah Myhill says that short periods of time in the sauna is all that is necessary as most chemicals come out within a few minutes of sweating. After being in the sauna it is also really important to shower and rehydrate with a mineral mix. http://drmyhill.co.uk/wiki/Detoxing_-_Far_Infrared_Sauna_(FIRS)
Stress Management is also very important
starting with doing what is necessary to get a better nights sleep and learning and practising stress reduction and management techniques such as MINDFULNESS
Your diet can't heal you but it can worsen your symptoms or it can reduce your symptoms
An unhealthy diet can increase inflammation and pain and a healthy diet if not adjusted for food intolerance if applicable (usually is with people with MCS) can increase inflammation and pain. The most common type of food intolerance experience by people with MCS is pharmacological food intolerance (causes psychological and system wide symptoms), some also experience FODMAP saccharide (sugar) intolerance causes uncomfortable bloating and other irritable bowel syndrome symptoms - to find out more start with the background behind my recipes at www.50symptoms.gone
Managing MCS without support and help (particularly if very severe and disabling) can be quite difficult
if you do not have help and support at home, find support through your local MCS support organisation and on line.
Dr Bradford Recommends that prior to engaging in any form of treatment a number of resources by Dr Grace Ziem should be read
The following is the recommended reading found at his site: http://www.dr-bradford.com/Ziem-Protocol.htmlrecommends patients read the following
Glutathione is the body's important antioxidant and detoxifying molecule, needed in higher amounts in chemical injury. Commercial oral forms are not absorbed, but a new oral form, S-acetyl Glutathione, is now available that is absorbed directly into the blood stream (contact me for details).
SpectraCell Comprehensive Nutritional Panel (cultured lymphocytes) testing
Intestinal healing is essential to health
Oral forms of healing substances, and sublingual MethylCobalamine (the active form of B12)
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2. Woolfe, J. Clifford (March 2012) Central sensitization: Implications for the diagnosis and treatment of pain
3. Ziem, G. Letter to Patients
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8. Nussbaumer, Linda, South Dakota State University Multiple Chemical Sensitivity Implications VOL. 03 ISSUE 4
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19. The Role of Food Intolerance in Chronic Fatigue SyndromeRobert H. Loblay, MD, PhD1 and Anne R. Swain, PhD21Senior Lecturer in Immunology, University of Sydney and Director, Allergy Service, Department of Clinical Immunology, Royal Prince Alfred Hospital 2Research Dietitian, Allergy Service, Royal Prince Alfred Hospital, Sydney, Australia
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